CURRICULUM VITAE

of

Tsvetelina Batsalova

(Assistant Professor)
Contact Address:

 

 Office address:
Department of Developmental Biology
Faculty of Biology
Plovdiv University "P. Hilendarski"
24, Tsar Assen Str.
BG-4000 Plovdiv
BULGARIA

e-mail: tsvetelina @ uni-plovdiv.bg

Date of Birth:  December 26th, 1983
Place of Birth: Gotse Delchev, BULGARIA
Nationality: Bulgarian
Education and training: March 2009 – February 2012: PhD student in Cell Biology
Department of Developmental Biology, Faculty of Biology, Plovdiv University "P. Hilendarski", Plovdiv, Bulgaria.

October 2005 – July 2006: M.Sc. in Cell Biology
Faculty of Biology,  Plovdiv University "P. Hilendarski", Plovdiv, Bulgaria.

October 2001 – July 2005: B.Sc. in Molecular Biology
Faculty of Biology,  Plovdiv University "P. Hilendarski", Plovdiv, Bulgaria.
Membership of Professional Institutions: Union of Scientists in Bulgaria
Swedish Society of Immunology
Languages Bulgarian - mother tongue
English  
Employment history:  

September 1st,  2011 – at present:		 Assistant Professor in Cell Biology.
Department of Developmental Biology, Faculty of Biology,  Plovdiv University "P. Hilendarski", Plovdiv, Bulgaria.
September 2010 – January 2011:
 Part-time Assistant Professor: Practicals in Cell Biology.
Department of Developmental Biology, Faculty of Biology,  Plovdiv University "P. Hilendarski", Plovdiv, Bulgaria.
May 2007 – December 2008:
 Guest-researcher:
Section of Medical Inflammation Research, Lund University/Karolinska Institute, Sweden.

2005 – 2006 		Lab technician:
Department of Developmental Biology, Faculty of Biology,  Plovdiv University "P. Hilendarski", Plovdiv, Bulgaria.

RESEARCH INTERESTS:
  		Cellular immunology, Autoimmunity and autoimmune diseases, Immunological tolerance, Immune-specific vaccination, Protein posttranslational modifications, T cells, TCR-MHC II interactions involved in disease development.
PARTICIPATION AT SCIENTIFIC PRACTICAL COURSES: April - June, 2009:
"Molecular and cellular mechanisms associated with autoimmune diseases", Karolinska Institute, Stockholm, Sweden.

August - September, 2010:
FEBS course on Techniques in Free Radical Biology, Debrecen, Hungary.


SCIENTIFIC PUBLICATIONS:  

1. Batsalova T., Dzhambazov B. 2009. Transfection, expression and purification of recombinant MHC class II proteins in SL2 insect cells.  Scientific researches of the Union of Scientists in Bulgaria - Plovdiv, series G, Medicine, Pharmacy and Dental medicine, Vol. XI, 142-145. ISSN  1311-9427

2. Batsalova T., Dzhambazov B. 2009. Functional characteristic of soluble recombinant MHC class II proteins.  Scientific researches of the Union of Scientists in Bulgaria - Plovdiv, series G, Medicine, Pharmacy and Dental medicine, Vol. XI, 146-149. ISSN  1311-9427

3. Batsalova T., Vestberg M., Holmdahl R., Dzhambazov B. 2010. MOG79-90 peptide in complex with recombinant MHC class II molecules ameliorates experimental autoimmune encephalomyelitis. - Biotechnology & Biotechnological Equipment, 24(2SE): 107-112.

4. Andersson I.E., Batsalova T., Dzhambazov B., Edvinsson L., Holmdahl R., Kihlberg J., Linusson A. 2010. Oxazole-modified glycopeptides that target arthritis-associated class II MHC A(q) and DR4 proteins. - Org. Biomol. Chem., 8(13): 2931-2940.

5. Batsalova T., Dzhambazov B., Merky P., Bäcklund A., Bäcklund J. 2010. Breaking T cell tolerance against self-type II collagen in HLA-DR4 transgenic mice and development of autoimmune arthritis. - Arthritis Rheum., 62(7): 1911-1920.

6. Batsalova T., Dzhambazov B., Klaczkowska D., Holmdahl R. 2010. Mice producing less reactive oxygen species are relatively resistant to collagen glycopeptide vaccination against arthritis.  - J. Immunol., 185(5): 2701-2709.

7. Merky P., Batsalova T., Bockermann R., Dzhambazov B., Sehnert B., Burkhardt H., Backlund J. 2010. Visualization and phenotyping of pro-inflammatory antigen-specific T cells during collagen induced arthritis in a mouse with a fixed collagen type II specific transgenic TCR beta chain. - Arthritis Res. Ther., 12(4): R155.

8. Ivanova A., Mikhova B., Batsalova T., Dzhambazov B., Kostova I. 2011. New furostanol saponins from Smilax aspera L. and their in vitro cytotoxicity. - Fitoterapia,  - Fitoterapia, 82(2): 282-287.

9. Andersson I.E., Andersson C.D., Batsalova T., Dzhambazov B., Holmdahl R., Kihlberg J., Linusson A. 2011. Design of glycopeptides used to investigate class II MHC binding and T-cell responses associated with autoimmune arthritis. PLoS ONE, 6(3): e17881.

10. Andersson I.E., Batsalova T., Haag S., Dzhambazov B., Holmdahl R., Kihlberg J., Linusson A. 2011. (E)-Alkene and Ethylene Isosteres Substantially Alter the Hydrogen-Bonding Network in Class II MHC Aq/Glycopeptide Complexes and Affect T-Cell Recognition. - J. Am. Chem. Soc., 133(36): 14368-14378.


BOOKS

1. Dzhambazov B., Batsalova T. 2010. Practicals in Cell Biology. University Press "Paisii Hilendarski", 80 p. (In Bulgarian) ISBN 978-954-423-643-4


Published abstracts of presentations at scientific congresses:

1. Batsalova T., Dzhambazov B., Klaczkowska D., Holmdahl R. 2010. Reduced reactive oxygen species influence the effectiveness of type II collagen glycopeptide vaccination against arthritis. - 14th International Congress of Immunology, Kobe, Japan, August 22-27, 2010.

2. Andersson D.C., Andersson I.E., Batsalova T., Dzhambazov B., Holmdahl R., Kihlberg J., Linusson A. 2010. An investigation of proteins involved in autoimmune arthritis by design and biological evaluation of chemical probes. 18th European Symposium on QSAR. “Discovery Informatics & Drug Design.”, Rhodes, Greece, September 19-24, 2010.

November 10, 2011