Balik Dzhambazov

	CURRICULUM VITAE of Balik Dzhambazov, PhD Professor
Contact Address:	Office address: Department of Developmental Biology Faculty of Biology Plovdiv University "P. Hilendarski" 24, Tsar Assen Str. BG-4000 Plovdiv BULGARIA Phones: +359-32-261535 or +359-32-261551 Mobile: +359-88-8415174 e-mail: balik@uni-plovdiv.net
Place of Birth:	Velingrad, BULGARIA
Nationality:	Bulgarian
Education and training:	June 1-st, 2001 – August 31-st, 2004: Postdoctoral position: Section for Medical Inflammation Research, Department of Cell and Molecular Biology, Medical Faculty, Lund University, Lund, Sweden. May 7-th, 2001 – PhD degree in Biology: Diploma # 27194, Council of Ministers, Higher Attestation Committee, Sofia, Bulgaria October 1-st, 1990 – July 26-th, 1995: B.Sc. and M.Sc. in Biology: Diploma VD-95 # 0005159, Faculty of Biology, University of Plovdiv, Plovdiv, Bulgaria.
Membership of Professional Institutions:	Member of the Bulgarian Union of Scientists
Languages:	Bulgarian /mother tongue/ English Russian
Employment history:
November 1, 2012 – at present:	Professor in Cell Biology: Lecturer in Cell Biology, Lecturer in Molecular Developmental Biology, Lecturer in Clinical Immunology, Lecturer in Bionanotechnologies; Department of Developmental Biology, Faculty of Biology, University of Plovdiv, Plovdiv, Bulgaria.
January 29, 2008 – October 31, 2012:	Associate Professor in Cell Biology: Lecturer in Cell Biology, Lecturer in Cytology, histology and embryology, Lecturer in Cell Cycle, Lecturer in Bionanotechnologies; Laboratory practice in Cell Biology, Laboratory practice in Cytology, histology and embryology, Laboratory practice in Cell Cycle, Department of Developmental Biology, Faculty of Biology, University of Plovdiv, Plovdiv, Bulgaria.
September 1, 2004 – January 29, 2008:	Senior Assistant Professor in Cell Biology: Lecturer in Cell Biology, Lecturer in Cytology, histology and embryology, Lecturer in Cell Cycle; Laboratory practice in Cell Biology, Laboratory practice in Cytology, histology and embryology, Laboratory practice in Cell Cycle, Department of Developmental Biology, Faculty of Biology, University of Plovdiv, Plovdiv, Bulgaria.
June 1, 2001 – August 31, 2004:	Postdoctoral position at Section for Medical Inflammation Research, Department of Cell and Molecular Biology, Medical Faculty, Lund University, Lund, Sweden.
October 1, 2000 – May 31, 2001:	Senior Assistant Professor in Cell Biology: Lecturer in Cytotoxicology, Laboratory practice in Cell Biology, Laboratory practice in Cytotoxicology, Department of Developmental Biology, Faculty of Biology, University of Plovdiv, Plovdiv, Bulgaria.
October 1, 1999 – September 30, 2000:	Senior Assistant Professor in Cell Biology: Lecturer in Signal Transduction, Laboratory practice in Cell Biology, Laboratory practice in Signal Transduction, Department of Developmental Biology, Faculty of Biology, University of Plovdiv, Plovdiv, Bulgaria.
November 1, 1996 – September 30, 1999:	Assistant Professor in Cell Biology: Laboratory practice in Cell Biology, Department of General Biology, Faculty of Biology, University of Plovdiv, Plovdiv, Bulgaria.
September 1, 1995 – October 31, 1996:	Financier: Municipality of Velingrad, Velingrad, Bulgaria.
RESEARCH INTERESTS:	Autoimmunity, Autoimmune diseases, Tolerance, Vaccines, Fusion proteins, T- and B-cell function, Antigen presentation, Animal models of rheumatoid arthritis and multiple sclerosis. In vitro cyto- and genotoxicology. Biological effects of plants' constituents on human and animal cell cultures in vitro. Antitumor activity of bioactive compounds. Karyological study of animal and plant cells.
HOBBY:	Traveling around the world. Visited places so far: Odessa (Ukraine), Budapest and Szeged (Hungary), Bucharest (Romania), Stockholm, Lund, Malmö, Göteborg, Helsingborg (Sweden), Copenhagen (Denmark), Paris (France), Rome, Venice and Milan (Italy), Berlin, Leipzig, Lichtenstein and Dresden (Germany), Oxford (United Kingdom), Prague (Czech Republic), Zurich (Switzerland), Gdansk (Poland), Crete (Greece), Valencia (Spain).
SCIENTIFIC PUBLICATIONS:	Please, see List of Publications in PubMed

SUPERVISED B.Sc. and M.Sc. STUDENTS

1. Vida Georgieva (Plovdiv University). 1998. Influence of different tissue culture media and serum concentrations on development and karyotype of FL-cells in vitro.
2. Adriana Monteva (Plovdiv University). 2001. Antitumour activity of Clinopodium vulgare L. extracts on cell cultures in vitro.
3. Radka Ivanova (Plovdiv University). 2001. Biological effects of natural products on cell cultures in vitro.
4. Gyulshen Feizula (Plovdiv University). 2002. Morphological variability and karyotype characterization of Scenedesmus bernardii and S. nygaardii (Chlorophyta) in clonal cultures.
5. Anne Honkanen (Lund University). 2004. The role of posttranslational modifications of type II collagen for recognition of the T-cell epitope CII 259-273 in collagen-induced arthritis.
6. Philip Ulfhake (Lund University). 2005. Therapy of autoimmune diseases using a MHC class II / peptide complex.
7. Kristina Monteva (Plovdiv University). 2005. Chromosome aberrations in mouse lymphocytes stimulated with Con-A.
8. Vladimir Staykov (Plovdiv University). 2008. Humoral response and immunodominant epitopes in rheumatoid arthritis.
9. Miglena Petrova (Plovdiv University). 2012. Role of the membrane transporters for the cytotoxic effect of the cyanotoxin microcystin-LR.
10. Manuela Skakova (Plovdiv University). 2012. In vitro cytotoxic and antioxidant activity of extracts from Fischerella major (Cyanoprokaryota).

SUPERVISED PhD STUDENTS

1. Tsvetelina Batsalova (March 1, 2009 - February 29, 2012). The role of MHC II and posttranslational modifications of type II collagen in the pathogenesis of rheumatoid arthritis. (Defence: January 26, 2012)
2. Todor Angelov Chaushev (March 1, 2012 - February 29, 2016). Establishment of an in vitro 3D cell model for investigation of the human endometrial receptivity.
3. Vladimir Todorov Staykov (March 1, 2012 - February 29, 2016). Derivation of male gametes from human embryonic stem cells.

COMMISSION OF TRUST

Ad-hoc reviewer for the following journals:

    - Journal of Immunology,
    - Molecular Biology Reports,
    - European Journal of Immunology,
    - Arthritis Research & Therapy,
    - EurAsian Journal of BioSciences,
    - Botanica Marina (Cytogenetics),
    - Revista de biologia marina y oceanografia (Cytogenetics),
    - Environmental Monitoring and Assessment.

Reviewer for the National Research Foundation of South Africa.
Reviewer for the National Science Fund of Bulgaria.

Member of the Academic Council at Plovdiv University (2011-2015).
Vice Dean of the Biological Faculty at Plovdiv University (2011-2015).

Published abstracts of presentations at scientific congresses:

1. Dhzambazov B., V. Georgieva, N. Popov, M. Draganov, 1997. Influence of two tissue culture media and different concentrations of normal calf serum on the development of FL cell culture in vitro. - First Balkan Congress of Medicine and Dentistry for Students and Young Doctors. Plovdiv, Bulgaria, 23-25 October 1997. - Folia medica, 39: 38-39.

2. Dzhambazov B., D. Belkinova, R. Mladenov, 2000. Karyotype study of Scenedesmus obliquus (Turp.) Kutzing and Scenedesmus obtusiusculus Chodat in Clonal cultures in vitro. - Second Balkan Botanical Congress, Istanbul, Turkey, 14-18 May, 2000.

3. Mladenov R., E. Hegewald, B. Dzhambazov, D. Belkinova, 2000. Ontogenetic changes in clonal cultures of Scenedesmus regularis Svirenko. - Second Balkan Botanical Congress, Istanbul, Turkey,14-18 May, 2000.

4. Teneva I., Dzhambazov B., Mladenov R., Schirmer K. 2002. In vivo and in vitro toxicology of the freshwater cyanobacterium Lyngbya aerugineo-coerulea. - 40th Congress of the European Societies of Toxicology (EUROTOX). Budapest, Hungary, 15-18 September 2002. - Toxicology Letters, 135 (Suppl. 1): S146-S147.

5. Dzhambazov B., Vestberg M., Holmdahl R. 2002. Molecular interactions between Major Histocompatibility Complex class II and T cell receptor in arthritis. - Third National Conference of the NIR, Workshop F "Applications of cell signaling", Lund, Sweden, 29 Sept - 1 Oct 2002.

6. Schirmer K., Teneva I., Dzhambazov B., Mladenov R. 2003. Cyanobacteria - an in vitro approach to studying their toxic potential to mammals and fish. - SETAC Europe 13th Annual Meeting, Society of Environmental Toxicology and Chemistry, Hamburg, Germany, 27 April - 1 May 2003.

7. Dzhambazov B., Vestberg M., Bockermann R., Holmdahl R. 2003. Soluble peptide-MHC II complexes prevent collagen-induced arthritis and experimental allergic encephalomyelitis. - Eric K. Fernström Jubilee Symposium "Functional genomics and inflammatory diseases", Ystad, Sweden, October 23-25, 2003.

8. Wichmann G., Weiss C., Herbarth O., Strauch G., Dzhambazov B., Teneva I., Schirmer K., Lehmann I. 2003. Water of the river Saale express strong stimulatory effects on cytokine production of human leukocytes. - Proceedings of the 11-th International Symposium On Toxicity Assessment - Vilnius, Lithuania, June 1-6, 2003: p. 94.

9. Dzhambazov B., Holmdahl R. 2004. Posttranslational Modifications of the Immunodominant T Cell Epitope of Bovine Type II Collagen Derived from Different Cartilage Tissues. - 12th International Congress of Immunology and 4th Annual Conference of FOCIS, Montreal, Canada, 18-23 July, 2004.

10. Dzhambazov B., Holmdahl R. 2005. Therapeutic vaccination of experimentall autoimmune encephalomyelitis by myelin oligodendrocyte glycoprotein in complex with MHC class II molecules. - New Approaches to Vaccine Development. From the bench to the field. - Vaccine Congress, Berlin, Germany, September 8-10, 2005.

11. Lavasani S., Fak F., Dzhambazov B., Alenfall J., Westrom B. 2006. Suppression of experimental autoimmune encephalomyelitis (EAE) by oral administration of Lactobacillus paracasei DSM 13434. - Annual meeting of the American Gastroenterological Association Institute and Digestive Disease Week, Los Angeles, California, USA, May 20-25, 2006. - GASTROENTEROLOGY 130 (4): Suppl. 2, A99-A99.

12. Teneva I., Mladenov R., Dzhambazov B. 2009. Toxicity evaluation of the filamentous freshwater cyanobacterium Pseudanabaena galeata Böcher. - SETAC Europe 19th Annual Meeting, Society of Environmental Toxicology and Chemistry, Göteborg, Sweden, 31 May - 4 June 2009.

13. Batsalova T., Dzhambazov B., Klaczkowska D., Holmdahl R. 2010. Reduced reactive oxygen species influence the effectiveness of type II collagen glycopeptide vaccination against arthritis. - 14th International Congress of Immunology, Kobe, Japan, August 22-27, 2010.

14. Andersson D.C., Andersson I.E., Batsalova T., Dzhambazov B., Holmdahl R., Kihlberg J., Linusson A. 2010. An investigation of proteins involved in autoimmune arthritis by design and biological evaluation of chemical probes. 18th European Symposium on QSAR. “Discovery Informatics & Drug Design.”, Rhodes, Greece, September 19-24, 2010.

BOOKS

1. Draganov M., Dzhambazov B., Popov N. 1997. Cell Biology (Laboratory practicals). VAP, 210 p. (In Bulgarian) ISBN 954-9806-02-2
2. Draganov M., Dzhambazov B., Popov N., Karnev G. 1999. Cytology (Laboratory practicals).VAP, 130 p. (In Bulgarian) ISBN 954-9806-12-X
3. Popov N., Tomova E., Dzhambazov B. 2008. Cytology, histology and embryology. University Press "Paisii Hilendarski", 302 p. (In Bulgarian) ISBN 978-954-423-465-2
4. Dzhambazov B., Batsalova T. 2010. Practicals in Cell Biology. University Press "Paisii Hilendarski", 80 p. (In Bulgarian) ISBN 978-954-423-643-4

PATENT

Holmdahl R., Kihlberg J., Dzhambazov B., Vestberg M. 2007. A COMPOUND COMPRISING AN AUTOANTIGENIC PEPTIDE AND A CARRIER WITH A MHC BINDING MOTIF. Patent number: WO/2007/058587 A1

November 04, 2012